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Saul Tzipori
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Clinical Significance of Respiratory Involvement in Cryptosporidiosis: Cross-Sectional Study of Children with Diarrhea and Respiratory Symptoms in Uganda.
Mor SM, Ndeezi G, Ascolillo LR, Tasimwa HB, Attipa C, Sponseller J, Mukunya D, Nakato R, Kayondo LN, Tzipori S, Tumwine JK, Griffiths JK
Am J Trop Med Hyg, tpmd240112, 13 Aug 2024
Cited by: 0 articles | PMID: 39137770
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PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections.
Shepard RM, Ghebremedhin A, Pratumchai I, Robinson SR, Betts C, Hu J, Sasik R, Fisch KM, Zak J, Chen H, Paradise M, Rivera J, Amjad M, Uchiyama S, Seo H, Campos AD, Dayao DA, Tzipori S, Piedra-Mora C, [...] Varner JA
Sci Transl Med, 16(754):eadi6887, 03 Jul 2024
Cited by: 0 articles | PMID: 38959328 | PMCID: PMC11272418
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Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus.
Greigert V, Saraav I, Son J, Zhu Y, Dayao D, Antia A, Tzipori S, Witola WH, Stappenbeck TS, Ding S, Sibley LD
Gut Microbes, 16(1):2297897, 08 Jan 2024
Cited by: 6 articles | PMID: 38189373 | PMCID: PMC10793699
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Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies.
Debatis M, Danz H, Tremblay JM, Gaspie K, Kudej RK, Vigdorovich V, Sather N, Jaskiewicz JJ, Tzipori S, Shoemaker CB
PLoS One, 18(11):e0291937, 27 Nov 2023
Cited by: 1 article | PMID: 38011121
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Co-administration of an effector antibody enhances the half-life and therapeutic potential of RNA-encoded nanobodies.
Thran M, Pönisch M, Danz H, Horscroft N, Ichtchenko K, Tzipori S, Shoemaker CB
Sci Rep, 13(1):14632, 05 Sep 2023
Cited by: 1 article | PMID: 37670025 | PMCID: PMC10480410
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Cryptosporidiuminfection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus
Greigert V, Saraav I, Son J, Dayao D, Antia A, Tzipori S, Witola WH, Stappenbeck TS, Ding S, Sibley LD
bioRxiv, 30 Aug 2023
Cited by: 0 articles | PPR: PPR716924
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A highly antigenic fragment within the zoonotic Cryptosporidium parvum Gp900 glycoprotein (Domain 3) is absent in human restricted Cryptosporidium species.
Dayao DAE, Jaskiewicz JJ, Sheoran AS, Widmer G, Tzipori S
PLoS One, 18(8):e0287997, 17 Aug 2023
Cited by: 0 articles | PMID: 37590269 | PMCID: PMC10434960
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Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease.
Gilbert IH, Vinayak S, Striepen B, Manjunatha UH, Khalil IA, Van Voorhis WC, Cryptosporidiosis Therapeutics Advocacy Group CTAG, Cryptosporidiosis Therapeutics Advocacy CTAG
BMJ Glob Health, 8(8):e012540, 01 Aug 2023
Cited by: 4 articles | PMID: 37541693 | PMCID: PMC10407372
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Scalable cryopreservation of infectious Cryptosporidium hominis oocysts by vitrification.
Jaskiewicz JJ, Dayao DAE, Girouard D, Sevenler D, Widmer G, Toner M, Tzipori S, Sandlin RD
PLoS Pathog, 19(6):e1011425, 08 Jun 2023
Cited by: 1 article | PMID: 37289815 | PMCID: PMC10284403
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Giardia duodenalis in Ugandan Children Aged 9-36 Months in Kampala, Uganda: Prevalence and Associated Factors.
Ndeezi G, Mor SM, Ascolillo LR, Tasimwa HB, Nakato R, Kayondo LN, Tzipori S, Mukunya D, Griffiths JK, Tumwine JK
Am J Trop Med Hyg, 109(1):147-152, 30 May 2023
Cited by: 2 articles | PMID: 37253438 | PMCID: PMC10324004
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Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies
Debatis M, Danz H, Tremblay JM, Gaspie K, Kudej RK, Vigdorovich V, Sather N, Jaskiewicz JJ, Tzipori S, Shoemaker CB
bioRxiv, 18 May 2023
Cited by: 0 articles | PPR: PPR661807
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Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis.
Hulverson MA, Choi R, Schaefer DA, Betzer DP, McCloskey MC, Whitman GR, Huang W, Lee S, Pranata A, McLeod MD, Marsh KC, Kempf DJ, LeRoy BE, Zafiratos MT, Bielinski AL, Hackman RC, Ojo KK, Arnold SLM, Barrett LK, [...] Van Voorhis WC
Antimicrob Agents Chemother, 67(4):e0142522, 15 Mar 2023
Cited by: 1 article | PMID: 36920244 | PMCID: PMC10112232
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A Simian Immunodeficiency Virus-Infected Macaque Model of Enterocytozoon bieneusi Infection.
Singh I, Tzipori S
AIDS Res Hum Retroviruses, 39(2):76-83, 25 Jan 2023
Cited by: 0 articles | PMID: 36424832 | PMCID: PMC9942168
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Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies
Debatis M, Danz H, Tremblay J, Gaspie K, Kudej R, Vigdorovich V, Sather N, Jaskiewicz J, Tzipori S, Shoemaker C
PLoS One, 18(11), 01 Jan 2023
Cited by: 0 articles | PMCID: PMC10681176
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A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits.
Zeng Y, Jiang M, Robinson S, Peng Z, Chonira V, Simeon R, Tzipori S, Zhang J, Chen Z
Bioengineering (Basel), 9(10):511, 27 Sep 2022
Cited by: 1 article | PMID: 36290479 | PMCID: PMC9598796
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Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917.
Gelfat I, Aqeel Y, Tremblay JM, Jaskiewicz JJ, Shrestha A, Lee JN, Hu S, Qian X, Magoun L, Sheoran A, Bedenice D, Giem C, Giem C, Manjula-Basavanna A, Pulsifer AR, Tu HX, Li X, Minus ML, Osburne MS, [...] Joshi NS
PLoS Pathog, 18(9):e1010713, 15 Sep 2022
Cited by: 4 articles | PMID: 36107831 | PMCID: PMC9477280
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Correction: The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp.
Fernández Álvaro E, Voong Vinh P, de Cozar C, Willé DR, Urones B, Cortés A, Price A, Tran Do Hoang N, Ha Thanh T, McCloskey M, Shaheen S, Dayao D, Martinot A, de Mercado J, Castañeda P, García-Perez A, Singa B, Pavlinac P, Walson J, [...] Baker S
Elife, 11:e83117, 05 Sep 2022
Cited by: 0 articles | PMID: 36063387 | PMCID: PMC9444238
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Pregnant sows immunized with Cryptosporidium parvum significantly reduced infection in newborn piglets challenged with C. parvum but not with C. hominis.
Sheoran A, Carvalho A, Mimbela RP, South A, Major S, Ginese M, Girouard D, Tzipori S
PLoS Negl Trop Dis, 16(7):e0010690, 29 Jul 2022
Cited by: 2 articles | PMID: 35905106 | PMCID: PMC9365126
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Development of Two Mouse Models for Vaccine Evaluation against Cryptosporidiosis.
Dayao DA, Jaskiewcz J, Lee S, Oliveira BC, Sheoran A, Widmer G, Tzipori S
Infect Immun, 90(7):e0012722, 23 Jun 2022
Cited by: 2 articles | PMID: 35735982 | PMCID: PMC9302090
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Reduced SARS-CoV-2 disease outcomes in Syrian hamsters receiving immune sera: Quantitative image analysis in pathologic assessments.
Piedra-Mora C, Robinson SR, Tostanoski LH, Dayao DAE, Chandrashekar A, Bauer K, Wrijil L, Ducat S, Hayes T, Yu J, Bondzie EA, McMahan K, Sellers D, Giffin V, Hope D, Nampanya F, Mercado NB, Kar S, Andersen H, [...] Martinot AJ
Vet Pathol, 59(4):648-660, 06 May 2022
Cited by: 1 article | PMID: 35521761
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The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp.
Fernández Álvaro E, Voong Vinh P, de Cozar C, Willé DR, Urones B, Cortés A, Price A, Tran Do Hoang N, Ha Thanh T, McCloskey M, Shaheen S, Dayao D, Martinot A, de Mercado J, Castañeda P, García-Perez A, Singa B, Pavlinac P, Walson J, [...] Baker S
Elife, 11:e69798, 15 Mar 2022
Cited by: 5 articles | PMID: 35289746 | PMCID: PMC8959600
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Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917
Gelfat I, Aqeel Y, Tremblay JM, Jaskiewicz JJ, Shrestha A, Lee JN, Hu S, Qian X, Magoun L, Sheoran A, Bedenice D, Giem C, Manjula-Basavanna A, Osburne MS, Tzipori S, Shoemaker CB, Leong JM, Joshi NS
bioRxiv, 18 Jun 2021
Cited by: 0 articles | PPR: PPR359043
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Identification and characterization of a new 34 kDa MORN motif-containing sporozoite surface-exposed protein, Cp-P34, unique to Cryptosporidium.
Jaskiewicz JJ, Tremblay JM, Tzipori S, Shoemaker CB
Int J Parasitol, 51(9):761-775, 25 Mar 2021
Cited by: 8 articles | PMID: 33774040 | PMCID: PMC8373667
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Repurposing tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively-drug resistant (XDR) Shigella spp.
Alvaro EF, Cozar Cd, Urones B, Cortés A, Price A, Hoang NTD, Tuyen HT, McCloskey M, Shaheen S, Dayao D, Mercado Jd, García-Perez A, Singa B, Pavlinac P, Walson J, Martínez-Martínez MS, Arnold S, Tzipori S, Ballel L, Baker S
Research Square, 24 Mar 2021
Cited by: 0 articles | PPR: PPR302649
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One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases.
Van Voorhis WC, Hulverson MA, Choi R, Huang W, Arnold SLM, Schaefer DA, Betzer DP, Vidadala RSR, Lee S, Whitman GR, Barrett LK, Maly DJ, Riggs MW, Fan E, Kennedy TJ, Tzipori S, Doggett JS, Winzer P, Anghel N, [...] Ojo KK
Vet Parasitol, 289:109336, 15 Dec 2020
Cited by: 10 articles | PMID: 33418437 | PMCID: PMC8582285
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Clinical Significance of Respiratory Involvement in Cryptosporidiosis: Cross-Sectional Study of Children with Diarrhea and Respiratory Symptoms in Uganda.

PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections.

Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus.

Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies.

Co-administration of an effector antibody enhances the half-life and therapeutic potential of RNA-encoded nanobodies.

Cryptosporidiuminfection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus

A highly antigenic fragment within the zoonotic Cryptosporidium parvum Gp900 glycoprotein (Domain 3) is absent in human restricted Cryptosporidium species.

Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease.

Scalable cryopreservation of infectious Cryptosporidium hominis oocysts by vitrification.

Giardia duodenalis in Ugandan Children Aged 9-36 Months in Kampala, Uganda: Prevalence and Associated Factors.

Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies

Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis.

A Simian Immunodeficiency Virus-Infected Macaque Model of Enterocytozoon bieneusi Infection.

Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies

A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits.

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917.

Correction: The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp.

Pregnant sows immunized with Cryptosporidium parvum significantly reduced infection in newborn piglets challenged with C. parvum but not with C. hominis.

Development of Two Mouse Models for Vaccine Evaluation against Cryptosporidiosis.

Reduced SARS-CoV-2 disease outcomes in Syrian hamsters receiving immune sera: Quantitative image analysis in pathologic assessments.

The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp.

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

Identification and characterization of a new 34 kDa MORN motif-containing sporozoite surface-exposed protein, Cp-P34, unique to Cryptosporidium.

Repurposing tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively-drug resistant (XDR) Shigella spp.

One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases.

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