Cow urine distillate as bioenhancer

Cow (Bos indicus) urine/gomutra has been elaborately explained in Ayurveda and described in “Sushruta Samhita”, “Ashtanga Sangraha” and other Ayurvedic texts as an effective medicinal substance/secretion of animal origin with innumerable therapeutic properties.[1] Bhav Prakash Nighantu describes gomutra as the best of all types of animal urine (including human) and enumerates its various therapeutic uses.[2] Persons who drink gomutra regularly are said to live a healthy life, remaining unaffected by the vagaries of old age, even at age 90.[3] Gomutra is called “Sanjivani” and “Amrita” in Ayurveda. In addition, it has applications as a biopesticide in organic farming along with cow dung, cow’s milk and other herbal ingredients.


Cow urine distillate as bioenhancer
Sir, In the "Journal of Ayurveda and Integrative Medicine" April 2010, 1 (2), the article on "Bioenhancers -Revolutionary concept in market" is very aptly written. In addition to the herbal bioenhancers elucidated in the article, I would like to add that cow urine distillate/concentrate (Kamdhenu Ark) shares this property too.
Cow (Bos indicus) urine/gomutra has been elaborately explained in Ayurveda and described in "Sushruta Samhita", "Ashtanga Sangraha" and other Ayurvedic texts as an effective medicinal substance/secretion of animal origin with innumerable therapeutic properties. [1] Bhav Prakash Nighantu describes gomutra as the best of all types of animal urine (including human) and enumerates its various therapeutic uses. [2] Persons who drink gomutra regularly are said to live a healthy life, remaining unaffected by the vagaries of old age, even at age 90. [3] Gomutra is called "Sanjivani" and "Amrita" in Ayurveda. In addition, it has applications as a biopesticide in organic farming along with cow dung, cow's milk and other herbal ingredients.
Gomutra is not a toxic waste material. 95% of it is water, 2.5% consists of urea, and the remaining 2.5% is a mixture of minerals, salts, hormones and enzymes. [4] Gomutra exhibits the property of Rasayana tattwa responsible for modulating various bodily functions, including immunity. It augments B-and T-lymphocyte blastogenesis; and IgG, IgA and IgM antibody titers in mice. It also increases secretion of interleukin-1 and interleukin-2, [5] phagocytic activity of macrophages, and is thus helpful in the prevention and control of infections. Antimicrobial and germicidal properties of gomutra are due to the presence of urea (strong effect), creatinine, swarn kshar (aurum hydroxide), carbolic acid, other phenols, calcium and manganese; its anticancer effect is due to uric acid's antioxidant property and allantoin; immunity is improved by swarn kshar; and wound healing is promoted by allantoin. Cardiovascular health is maintained by a number of its components: kallikrein is a vasodilator; the enzyme urokinase acts as a fibrinolytic agent; nitrogen, uric acid, phosphates and hippuric acid act as diuretic agents; ammonia maintains the integrity of blood corpuscles; nitrogen, sulfur, sodium and calcium components act as blood purifiers; while iron and erythropoietin stimulating factor maintain hemoglobin levels. Renal health is maintained by nitrogen, which acts as a renal stimulant, and urinary components which act as diuretic agents. Its antiobesity effect is due to the presence of copper ions; calcium promotes skeletal/bone health. Aurum hydroxide and copper act as antidotes for various poisons in the body. [6] Certain poisons can be refined and purified if soaked in gomutra for 3 days. For example, Dhatura (Dhatura metel) seeds (with shell peeled off) are considered purified after soaking in gomutra for 12 hours. Cow urine can be used for purification of guggul (Comniphera mukul), loha (iron) and bhalataka (Semecarpus anacardium), detoxification of aconite (Aconitum napellus) and also for purification and detoxification of silver. [7] Bioenhancing is one of its many properties. [8] Cow urine distillate is more effective as a bioenhancer than cow urine, and increases the effectiveness of antimicrobial, antifungal and anticancer drugs. [9] It also increases the activity of gonadotropin releasing hormone conjugate with bovine serum albumin (GnRH-BSA) and zinc. [10] Cow urine has bioenhancing activity for Rifampicin, the front-line anti-tubercular drug used against tuberculosis, increasing its action up to sevenfold against Escherichia coli, and up to 11-fold against Gram-positive bacteria. Cow urine distillate enhances the transport of antibiotics, e.g., Rifampicin, Tetracycline, and Ampicillin, across the gut wall as well as across artificial membranes. Transport enhancement varies from approximately twofold to sevenfold. [11] The GnRH-BSA conjugate has a deleterious effect on reproductive hormones and estrous cycles of female mice; cow urine concentrate acts as a bioenhancer of immunization efficacy to modulate these effects. [10] Cow urine exhibits antitoxic activity against cadmium chloride and can be used as a bioenhancer for zinc, Zn 2+ . Mature male mice, Mus musculus, exposed to cadmium chloride only, showed 0% fertility rate. However, the animals given a combination of cadmium chloride + cow urine + zinc sulfate showed 90% fertility rate with 100% viability and lactation indices. Besides this, the fertility index was also found to be 88% in the group treated with cadmium chloride and cow urine. [12] Cow urine has been granted US Patents (No. 6,896,907

A traditional way of rice preparation with particular benefits for Arthritis and musculo-skeletal disorders
Sir, The review paper by Chopra in J-AIM [1] concerning Ayurveda drugs for Arthritis is clearly of great value to those who have contracted the disease, but in order to be considered full Ayurveda treatments, such drugs need to be combined with diet and lifestyle recommendations appropriate to the patient. In this sense the studies concerned are not really about Ayurveda as practiced, but about a bowdlerized Ayurveda seen from the biomedical perspective, with its treatments implemented and evaluated strictly as a substitution for western medicine. This constitutes a sad failure to acknowledge Ayurveda's unique features which promise to give it a highly valued place in medicine globally.
Diet and lifestyle components of Ayurveda are fundamental, and, as is well known, Ayurveda states that even the administration of the correct medicine to cure a complaint may not be of lasting value unless the lifestyle and diet of the patient are attended to. Most chronic illnesses or degenerative diseasees like arthritis result from persistent stresses placed on the system by personal habits which, in the long term, build into unacceptable strain on regulatory function. Over the years, such strain drives the system to breaking point, and pathology results.
Ayurveda is clear that diet and lifestyle have to be attended to. Without such action, say its texts, disease will inevitably return. To implement this, the vaidya plays the role of 'doctor' in the true sense of the word's Latin root, 'docere', meaning 'to teach'. Ayurveda traditional treatments incorporate components of instruction in remedial diet and so on, to help bring the patient's regulatory system back to whatever state of relative equilibrium can still be regained after years of misuse. If the patient's system is strong, however, such remedial instruction can often be of actual curative value.
Knowledge of good dietary practices was deeply embedded in India's traditional culture. Earlier generations often observed age-old procedures for doing particular things for reasons they did not fully understand, but did out