Insomnia is a highly prevalent disorder in the US and worldwide. Insomnia is defined as the presence of long sleep latency, frequent nocturnal awakenings, or prolonged periods of wakefulness during the sleep period, or even frequent transient arousals. Zaleplon is a medication used in the management and treatment of insomnia. It is in the hypnotic class of drugs but is unrelated to benzodiazepines, barbiturates. This activity reviews the indications, actions, and contraindications for zaleplon when using it as a valuable agent in managing insomnia.