CD14 and mastitis: Association study was conducted for different variants of CD14 with mastitis in buffalo, detected through somatic cell count, california mastitis test.<bold>Result:</bold> Eight variants of CD14 were detected and mutational hotspots were detected in bubaline CD14 with 58 number of non-synonymous SNP, out of which 18 were observed to be deleterious and 34 as thermodynamically unstable.