Children were divided into euthyroid (n=88) and euthyroid sick syndrome(ESS)groups (n=106).<bold>Results: </bold>The ESS group had a higher level of white blood cell count (WBC), plasma glucose (PG), beta-hydroxybutyric acid (β-HB), triglyceride (TG), anion gap (AG), glycosylated hemoglobin (HbA1c) and a lower level of HCO<sub>3</sub><sup>-</sup>, prealbumin (PA), and albumin (ALB) compared with the euthyroid group (P<0.05). The gene discussed is TTR; the disease is endometrioid stromal sarcoma.