SPN and thalassemia: Furthermore, in vitro hematopoietic differentiation protocols successfully induced the iPSCs to generate CD34<sup>+</sup>/CD43<sup>+</sup> hematopoietic progenitors, which were functionally validated by their ability to form hematopoietic colonies in colony-forming unit (CFU) assays.<h4>Conclusion</h4>We have successfully derived and comprehensively characterized six patient-specific iPSC lines from intermediate α-thalassemia fetuses.