CD40LG and helminthiasis: The presence of helminth infections were associated with significantly higher anti-PGL-I IgM levels (<i>P</i> < 0.0001), with 22.4% of helminth-infected children testing seropositive compared to 8.8% of non-infected children (<i>P</i> < 0.001).<h4>Interpretation</h4>Our findings demonstrate a high anti-PGL-I IgM seroprevalence among rural, low-SES, and helminth-infected children in Indonesia, indicating elevated levels of <i>M.