IGHE and angioedema: IgG-aFcεRI levels correlated negatively with IgG-aIgE, neutrophil count, and total IgE, and positively with total IgG.<h4>Conclusion</h4>Higher IgG-aIgE levels were associated with angioedema, accompanying symptoms, omalizumab use, rural residence, and nighttime symptom patterns, suggesting an association with distinct clinical features of CSU.