AMR rate was graded from 0 to 3, and a mixed-effect continuation ratio was used for the analysis.<h4>Results</h4>Patients with oral cancer (OR 1.38, 95% CI 1.06-1.80), a history of smoking (OR 1.19, 95% CI 1.01-1.41), immunosuppressive therapy (OR 1.36, 95% CI 1.06-1.75), insulin-treated diabetes (OR 1.57, 95% CI 1.05-2.35), or cardiovascular disease (OR 1.28, 95% CI 1.02-1.61) had significantly higher risk of infection with MDR bacteria. The gene discussed is INS; the disease is cardiovascular disorder.