AGT and atrial fibrillation: For <i>in vivo</i> validation, an Ang II-infused mouse model with valsartan intervention was utilized, including transesophageal burst pacing, immunostaining, immunoblotting, and efferocytosis quantification.<h4>Results</h4>Plasma from AF patients exhibited an autonomic-imbalance signature (upregulated monoaminergic and downregulated cholinergic neurotransmitters).