Thirty-five pieces of best evidence were summarized across five domains: basic patient assessment and screening, blood glucose monitoring and target control, optimization of enteral nutrition regimens, insulin intervention strategies, and multidisciplinary collaborative management.<h4>Conclusion</h4>This study summarizes the best available evidence for GV management during EN in adult patients with cerebral infarction in the ICU. The gene discussed is INS; the disease is brain infarction.