IL10 and infection: This included the extraintestinal dissemination of SPtA, the inhibition of pro-inflammatory cytokines, and progressively worsening pathological changes over time following infection in <i>IL10<sup>-/-</sup></i> ASF mice.<h4>Conclusion</h4>The results of this study suggest that ASF mice represent a suitable low-cost model for investigating the pathogenesis of SPtA infection.