CLOCK and allergic disease: Integration with published atopic dermatitis transcriptomic studies, rather than new skin transcriptomic profiling in this study, suggested global clock downregulation alongside specific shifts involving ARNTL2, NOCT, and RORC.<h4>Conclusions</h4>These findings support pathway-level and candidate gene-level convergence between OCD and allergic diseases, centred on pruning biology and circadian regulation.