CXCR1 and medical procedure: This highlights the need to identify shared upstream pathways whose inhibition could suppress both responses simultaneously.<h4>Objective</h4>We sought to elucidate the role of CXCR1/2 in recruitment and proliferation of T<sub>H</sub>2 and T<sub>H</sub>17 cells during allergic airway inflammation.<h4>Methods</h4>Studies used mice sensitized and challenged with cat dander extract, inducing dual T<sub>H</sub>2/T<sub>H</sub>17 lung inflammation.