The probability of live birth in the GnRH-ant group was significantly higher than that in the PPOS group (odds ratio = 6.085, 95% confidence interval: 2.489-14.880, <i>P</i> < 0.001).<h4>Conclusion</h4>This study indicates that the GnRH-ant stimulation protocol is advantageous as compared to the PPOS protocol for infertile women with ARA undergoing controlled ovarian stimulation combined with frozen embryo transfer, as evidenced by improved embryological outcomes, higher CPRs, and higher LBRs. This evidence concerns the gene GNRH1 and Infertility.