FLT3 and acute myeloid leukemia: The objective of this mixed-methods study was to evaluate the rates of FLT3 testing and guideline-concordant treatment within a community health system, and to identify the clinical and systemic factors driving treatment decision-making.<h4>Methods</h4>A retrospective, mixed-methods cohort study was conducted using anonymized data from adult patients diagnosed and treated for AML between 2017 and 2024 within a multi-site community health system.