The aim of the study was to evaluate the expression of Ki-67 in DPE, EH without atypia, AEH, and EC, and to compare Ki-67 expression in low-grade and high-grade EC.<h4>Methodology</h4>A hospital-based cross-sectional study was conducted in the Histopathology Section of the Department of Pathology using endometrial tissue samples obtained by endometrial curettage and hysterectomy from patients diagnosed with DPE, hyperplastic endometrium, and EC. The gene discussed is MKI67; the disease is Hyperplasia of the endometrium.