Serum insulin-like growth factor 1 concentration was 75.9 ng/mL (SI: 9.95 nmol/L) (reference range, 94-284 ng/mL [SI: 12.3-37.2 nmol/L]), and growth hormone suppressed to 0.49 ng/mL (SI: 0.49 μg/L) following an oral glucose tolerance test, excluding acromegaly. This evidence concerns the gene GH1 and acromegaly.