In addition, C-reactive protein (CRP) partially mediated the snoring-reasoning ability association (PM: β = -0.071, p = 0.049), with MR analysis confirming a causal pathway, whereas snoring elevated CRP levels to impair reasoning, accounting for 32.1% of the observed relationship.<h4>Conclusion</h4>In this cohort study, abnormal sleep traits correlated with domain-specific cognitive impairments, with CRP partially mediating the snoring-reasoning association. The gene discussed is CRP; the disease is Cognitive impairment.