Mechanistic insights were gained using MeRIP-qPCR and RNA Pull-Down Assays to identify m<sup>6</sup>A modification sites on VEGFA mRNA.<h4>Results</h4>m<sup>6</sup>A levels and METTL14 expression were significantly downregulated in HCC tissues. The gene discussed is METTL14; the disease is hepatocellular carcinoma.