Specifically, we sought to determine whether METTL14 functions as a suppressor of HCC progression by restricting VEGFA-driven angiogenesis through an m<sup>6</sup>A-dependent mechanism.<h4>Methods</h4>Quantitative m<sup>6</sup>A levels were performed to compare modification levels between HCC tissues and paired normal tissues. This evidence concerns the gene VEGFA and hepatocellular carcinoma.