TLR7 and systemic lupus erythematosus: Understanding pathway-level similarities and differences between mouse models and human disease is essential, given the marked clinical and molecular heterogeneity of SLE.<h4>Methods</h4>Four spontaneous SLE mouse models were studied: MRL <i><sup>lpr/lpr</sup></i> , NZB/W, BXSB.<i>Yaa</i>, and Tlr7.Tg6.