CEACAM5 and neoplasm: Based on these findings, we developed a detection assay for CEACAM60 in fluids, which could serve as a basis for dynamic monitoring of tumor progression in animals in the future.<h4>Conclusion</h4>Considering the central roles of CEACAM1 and CEA in tumor immunotherapy and tumor surveillance in humans, porcine models with an increased predisposition for colorectal neoplasia may provide a valuable translational platform for the development and refinement of next-generation colorectal cancer immunotherapies.