METTL3 and Hepatic fibrosis: Hepatic fibrosis is a critical intermediate stage in this process, and METTL3-mediated m<sup>6</sup>A modification may represent an important post-transcriptional mechanism linking AFB<sub>1</sub>-induced liver injury to fibrogenic progression.<h4>Methods</h4>AFB<sub>1</sub>-induced hepatic fibrosis was evaluated using in vivo mouse models and in vitro cultured hepatic stellate cells (HSC).