IL18 and heart failure: The pooled mean difference was 251.59 pg/mL (95% CI: 177.24-325.93 pg/mL) with a random effects model.<h4>Conclusion</h4>Serum IL-17, IL-18 Th17, and Treg count have utility for risk stratification for patients with heart failure, as biomarkers for heart failure severity and potential target pathways for treatment.