In multivariate logistic regression, anti-SSA Ro60 kDa positivity was independently associated with a positive biopsy result (OR: 12.94; 95% CI: 1.39-120.13; p = 0.024), while myalgias were associated with a lower likelihood of biopsy positivity.<h4>Conclusion</h4>This exploratory study identified associations between serological markers and salivary gland biopsy findings in SS. This evidence concerns the gene TRIM21 and Myalgia.