In addition to zoonotic transmission, <i>Brucella</i> species are a well-recognized cause of laboratory-acquired infections (LAIs) among microbiology laboratory personnel.<h4>Methods</h4>We report a case of laboratory-acquired <i>Brucella abortus</i> infection in a young woman presenting with undulant fever, arthralgia, systemic inflammation, elevated ferritin levels, and antinuclear antibody (ANA) positivity. This evidence concerns the gene BTG3 and infection.