This study aimed to compare the expression of exosomal <i>HOTAIR</i>, <i>NEAT1</i>, <i>MALAT1</i>, <i>AFAP1-AS1</i>, <i>ANRIL</i>, and <i>HULC</i> lncRNAs in primary tumor tissue and blood of patients with sporadic TNBC to evaluate their potential as biomarkers. This evidence concerns the gene AFAP1 and neoplasm.