<i>Materials and Methods</i>: A total of 151 participants (MDD <i>n</i> = 41; BD <i>n</i> = 40; HC (healthy controls) <i>n</i> = 70) were profiled for 42 blood-derived parameters including composite inflammatory indices, hematological markers, trace elements measured by ICP-MS, and circulating BDNF and NLRP3 quantified by ELISA. This evidence concerns the gene BDNF and Behcet disease.