TP53 and endometrial carcinoma: <b>Background:</b> Endometrial carcinoma (EC) is now classified primarily by molecular subtype-<i>POLE</i>-ultramutated, mismatch repair-deficient (dMMR), <i>TP53</i>-mutant/copy-number-high (CNH), and "no specific molecular profile" (NSMP)-a framework that has reshaped prognostic counseling and adjuvant therapy decisions.