Two additional patients presenting with epidermolysis bullosa harbored truncating variants in <i>COL7A1</i> (c.497dup; p.Val168Glyfs12) and <i>EXPH5</i> (c.5786del; p.Pro1929Leufs8), respectively; the latter also carried a <i>KRT5</i> missense variant (c.1607G>A; p.Ser536Asn). Here, EXPH5 is linked to epidermolysis bullosa.