ASXL3 and Severe feeding difficulties - failure to thrive - microcephaly due to ASXL3 deficiency: <b>Background/Objectives</b>: Bainbridge-Ropers syndrome (BRPS) is a rare neurodevelopmental disorder caused by truncating and splicing pathogenic variants in the additional sex combs-like 3 (<i>ASXL3</i>) gene.