CCL20 and neoplasm: <b>Methods</b>: The biological and clinical significance of CCL20 was investigated through differential expression analysis, weighted gene co-expression network analysis, survival and clinicopathological association analyses, ROC-based diagnostic evaluation, immune infiltration and tumor microenvironment characterization, immune checkpoint correlation analysis, single-cell transcriptomic analysis, in silico knockout analysis, drug sensitivity prediction, molecular docking, and tissue microarray-based immunohistochemistry.