Survival analyses demonstrated that high expression of <i>CCNA2</i> and <i>S100A12</i>, and low expression of <i>ADRB2</i>, <i>ARRB1</i>, <i>PTGS2</i>, and <i>SMAD7</i> were significantly associated with poor overall survival in NSCLC patients.<h4>Conclusions</h4>These findings highlight potential biomarkers for prognosis and may inform future therapeutic strategies in Vietnamese NSCLC patients. Here, ARRB1 is linked to non-small cell lung carcinoma.