ANXA5 and neoplasm: Supernatants from non-stimulated and E2-stimulated CAFs were used to culture CC cells, and mitochondrial metabolism was measured by MTT, ROS production by H2DCFDA, migration using the wound-healing assay, apoptosis by Annexin V assay, and gene expression by next-generation RNA-seq.<h4>Results</h4>Stimulation of CC cells with CAFs' supernatants demonstrated that it influences tumor cells in different ways.