INS and type 2 diabetes mellitus: Additionally, gut microbiota composition and the levels of short-chain fatty acids were determined.<h4>Results</h4>ZJMP treatment significantly ameliorated hyperglycemia and dyslipidemia, elevated serum insulin levels, reduced intestinal mucosal permeability, and attenuated histopathological lesions in the heart, kidney, and pancreas of T2DM rats.