Evaluation demonstrated bilateral ground glass opacities with interstitial changes compatible with a nonspecific interstitial pneumonia pattern, echocardiographic findings concerning for pulmonary hypertension, Raynaud phenomenon, and autoimmune serologies including elevated polymyositis/scleroderma 75 (PM/Scl 75) and small nuclear ribonucleoprotein 70 kilodalton (SNRNP 70Kd) antibodies suggestive of a scleroderma-like autoimmune process. The gene discussed is LSM2; the disease is scleroderma.