INS and familial primary hypomagnesemia: These clinical manifestations were closely associated hypocalcemia, hypophosphatemia, hypomagnesemia, hypernatremia, hypokalemia, hypoferremia, and hypozincemia, hypoglycemia, decreased level of reduced glutathione (GSH) alongside elevation in serum creatine kinase (CK) and aspartate aminotransferase (AST) activities, malondialdehyde (MDA), circulating insulin (INS) and parathyroid hormone (PTH) concentrations.