Furthermore, C5orf46's association with other critical cancer features, for instance, cancer stemness, tumor epithelial-mesenchymal transition (EMT), and DNA repair, was also investigated.<h4>Results</h4>Firstly, the physicochemical properties, including amino acid composition, estimated molecular weight, and protein half-life, of the C5orf46 gene were computed sequentially. The gene discussed is C5orf46; the disease is cancer.