TGFB1 and thanatophoric dysplasia: Network and enrichment analyses revealed convergent biological pathways involving cellular and multicellular homeostasis, metal ion regulation, and TGF-β/BMP-associated signaling, linking miRNA-associated regulatory networks to erythroid and ironrelated processes.<h4>Discussion</h4>In conclusion, children with TD may exhibit homeostatic dysregulation of circulating miRNAs, erythroid profiles, and iron metabolism.