Mechanically, <i>in vitro</i> and <i>in vivo</i> experiments validate that valerate-induced upregulation of GABBR1 stimulates the secretion of CXCL13, which in turn promotes robust infiltration and activation of CD8<sup>+</sup> T cells within the tumor microenvironment. The gene discussed is GABBR1; the disease is neoplasm.