HAVCR1 and acute kidney injury: Meta-analysis showed that urinary KIM-1 has acceptable diagnostic accuracy (AUC = 0.76; 95% CI: 0.65 - 0.86) as an early biomarker for cisplatin-induced AKI.<h4>Conclusions</h4>KIM-1 is a proximal tubule-specific, injury-responsive biomarker that is upregulated early during cisplatin-induced kidney damage.