Here, we describe the immunomodulatory properties of IL6/1 fusokine and a method to deliver this fusokine to produce inhibition of ovarian tumor growth in a pre-clinical mouse model.<h4>Methods</h4>Lentiviral vectors encoding murine or human IL6/1 were designed using Vector Builder and expressed in either HEK293, CHO or ID8-F3 (p53<sup>-/-</sup>) cells depending on the downstream experiment to be conducted. This evidence concerns the gene TP53 and ovarian neoplasm.