The aim of this study was to assess angiopoietin-like protein-3 levels in polycystic ovary syndrome and to investigate the potential of angiopoietin-like protein-3 for discriminating metabolic syndrome in polycystic ovary syndrome.<h4>Methods</h4>A total of 50 women with polycystic ovary syndrome and 45 controls were included in this prospective study. Here, ANGPTL3 is linked to polycystic ovary syndrome.