Three unique clusters were determined: cluster 1 had higher BMI and lower HbA1c; cluster 2 had a higher HbA1c and was more likely to need insulin; and cluster 3 had a lower eGFR and more diabetes-related comorbidities.<h4>Conclusion</h4>yT2D have worse glycemic control, greater obesity, and similar renal decline compared with older adults with T2D. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.