INS and diabetes mellitus: Twice-daily rather than once-daily insulin therapy in canine DM has become more prevalent since the archive was founded.<h4>Limitations</h4>UKCDRA does not capture detailed information on concurrent diseases or DM environmental risk factors.<h4>Conclusion</h4>This study provides an update to an earlier UKCDRA report and demonstrates shared breed-associated risk factors for adult-onset non-dioestrus and female entire DM.