TMBIM4 and pneumonitis: Since the actions of FLU on the inflammatory components have not been elucidated, this study investigated its effects in a mouse model of interstitial pneumonitis.<h4>Methods</h4>Pneumonitis was induced in wild-type (WT) and S1R knockout (<i>S1r</i> <sup><i>-/-</i></sup> ) mice by intratracheal administration of lipopolysaccharide: 0.5 mg/kg LPS.