MGMTai: O6-methylguanine-DNA methyltransferase (&lt;i&gt;MGMT&lt;/i&gt;) methylation prediction in isocitrate dehydrogenase (&lt;i&gt;IDH&lt;/i&gt;)-wild type glioblastoma to direct temozolomide therapy. The gene discussed is MGMT; the disease is glioblastoma.