Signet-ring cell carcinoma (SC), a subtype associated with mucin-producing phenotypes and distinct molecular pathways, is infrequently encountered in this age group, particularly in low-resource settings.<h4>Presentation of case</h4>A 10-year-old boy presented with 1 month of right lower quadrant pain, progressive abdominal distension, anorexia, constipation, and weight loss. This evidence concerns the gene MUC5AC and signet ring cell carcinoma.