Meta-analyses on lipid-lowering drug target HMG-CoA reductase inhibitor (OR 0.66, 95% CI 0.53-0.82), serum vitamin D (OR 0.88, 95% CI 0.82-0.95), and dried fruit intake (HR 0.61, 95% CI 0.41-0.91) were supportive of protective associations.<h4>Conclusions</h4>Genetic evidence confirms OC risks associated with endometriosis, and age at menarche and menopause. This evidence concerns the gene HMGCR and endometriosis.