The primary imaging endpoint was defined as D. Following completion of MRI, renal function, histopathology, and expression of apoptosis markers (Bcl-2, Caspase-3), water channel protein aquaporin-3, and tight junction proteins (zonula occludens-1, occludin) were subsequently evaluated.<h4>Results</h4>Despite preserved conventional renal function, IVIM MRI detected early renal alterations 24 h after cardiac arrest. Here, CASP3 is linked to cardiac arrest.